嚴重急性呼吸系統綜合症相關冠狀病毒
（重定向自SARSr-CoV）
嚴重急性呼吸系統綜合症相關冠狀病毒
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病毒分類 
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| （未分级）： | 病毒 Virus |
| 域： | 核糖病毒域 Riboviria |
| 界： | 正核糖病毒界 Orthornavirae |
| 门： | 小核糖病毒门 Pisuviricota |
| 纲： | 小南嵌套病毒纲 Pisoniviricetes |
| 目： | 套式病毒目 Nidovirales |
| 科： | 冠状病毒科 Coronaviridae |
| 属： | 乙型冠狀病毒屬 Betacoronavirus |
| 亚属： | SARS乙型冠状病毒亚属 Sarbecovirus |
| 种： | 嚴重急性呼吸系統綜合症相關冠狀病毒 Severe acute respiratory
syndrome-related coronavirus |
| 病毒株 | |
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| 「SARS-CoV」的各地常用譯名 | |
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| 中国大陸 | 严重急性呼吸窘迫综合征相关病毒[1] |
| 臺灣 | 嚴重急性呼吸道症候群相關冠狀病毒 |
| 港澳 | 嚴重急性呼吸系統綜合症相關冠狀病毒 |
严重急性呼吸窘迫综合征相关病毒（英語：Severe acute respiratory syndrome–related coronavirus），簡稱SARS相关冠状病毒（SARSr-CoV），是冠狀病毒科乙型冠状病毒属的一个种。[2]该种病毒现有2个可传染人的分型[3]。
分型
- 第一个分型称为嚴重急性呼吸道症候群冠狀病毒1型（英語：Severe acute respiratory syndrome coronavirus 1，简称SARS-CoV-1）[3]，发现于2003年，引发了嚴重急性呼吸系統綜合症的疫情，有可能是通过菊头蝠传播到人类的[4]。
- 第二个分型称为嚴重急性呼吸道症候群冠狀病毒2型（英語：Severe acute respiratory syndrome coronavirus 2，简称SARS-CoV-2），发现于2019年，引发了2019冠状病毒病的疫情[3]，有研究认为，该病毒类型可能是通过马来穿山甲传播给人类的[5][6]。截至2021年6月，病毒溯源工作仍在进行[7]。統計至2021年2月4日為止，病例數約為SARS-CoV的12800倍，病逝人數約為2900倍。
- 關係圖
| 嚴重急性呼吸道症候群相關冠狀病毒 SARSr-CoV | |||||||||||||||||||||||||||
| 嚴重急性呼吸道症候群冠狀病毒1型 SARS-CoV-1 | 嚴重急性呼吸道症候群冠狀病毒2型 SARS-CoV-2 | ||||||||||||||||||||||||||
演化樹
截至2021年1月[update]，SARS-CoV與相關病毒株的系統發生樹：
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SARS-CoV-2 79 % | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
蝙蝠病毒
果子狸病毒
人類病毒
SARS-CoV-2與相關病毒株的系統發生樹[15][16] :
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SARS-CoV 79% | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
蝙蝠病毒
穿山甲病毒
人類病毒
参考文献
引用
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- ^ Hu, Ben; Zeng, Lei-Ping; Yang, Xing-Lou; Ge, Xing-Yi; Zhang, Wei; Li, Bei; Xie, Jia-Zheng; Shen, Xu-Rui; Zhang, Yun-Zhi. Drosten, Christian , 编. Discovery of a rich gene pool of bat SARS-related coronaviruses provides new insights into the origin of SARS coronavirus. PLOS Pathogens. 2017-11-30, 13 (11): e1006698 [2021-04-07]. ISSN 1553-7374. PMC 5708621
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- ^ Murakami, Shin; Kitamura, Tomoya; Suzuki, Jin; Sato, Ryouta; Aoi, Toshiki; Fujii, Marina; Matsugo, Hiromichi; Kamiki, Haruhiko; Ishida, Hiroho; Takenaka-Uema, Akiko; Shimojima, Masayuki; Horimoto, Taisuke. Detection and Characterization of Bat Sarbecovirus Phylogenetically Related to SARS-CoV-2, Japan. Emerging Infectious Diseases. 2020, 26 (12): 3025–3029. ISSN 1080-6040. doi:10.3201/eid2612.203386.
- ^ 18.0 18.1 Hu, Dan; Zhu, Changqiang; Ai, Lele; He, Ting; Wang, Yi; Ye, Fuqiang; Yang, Lu; Ding, Chenxi; Zhu, Xuhui; Lv, Ruicheng; Zhu, Jin; Hassan, Bachar; Feng, Youjun; Tan, Weilong; Wang, Changjun. Genomic characterization and infectivity of a novel SARS-like coronavirus in Chinese bats. Emerging Microbes & Infections. 2018, 7 (1): 1–10. ISSN 2222-1751. doi:10.1038/s41426-018-0155-5.
- ^ Lam, Tommy Tsan-Yuk; et al. Identifying SARS-CoV-2-related coronaviruses in Malayan pangolins. Nature. 2020, 583 (7815): 282–285. ISSN 0028-0836. doi:10.1038/s41586-020-2169-0.
- ^ Xiao, Kangpeng; Zhai, Junqiong; Feng, Yaoyu; Zhou, Niu; Zhang, Xu; Zou, Jie-Jian; Li, Na; Guo, Yaqiong; Li, Xiaobing; Shen, Xuejuan; Zhang, Zhipeng; Shu, Fanfan; Huang, Wanyi; Li, Yu; Zhang, Ziding; Chen, Rui-Ai; Wu, Ya-Jiang; Peng, Shi-Ming; Huang, Mian; Xie, Wei-Jun; Cai, Qin-Hui; Hou, Fang-Hui; Chen, Wu; Xiao, Lihua; Shen, Yongyi. Isolation of SARS-CoV-2-related coronavirus from Malayan pangolins. Nature. 2020-07-09, 583 (7815): 286–289. doi:10.1038/s41586-020-2313-x.
- ^ Zhou, Hong; Chen, Xing; Hu, Tao; Li, Juan; Song, Hao; Liu, Yanran; Wang, Peihan; Liu, Di; Yang, Jing; Holmes, Edward C.; Hughes, Alice C.; Bi, Yuhai; Shi, Weifeng. A Novel Bat Coronavirus Closely Related to SARS-CoV-2 Contains Natural Insertions at the S1/S2 Cleavage Site of the Spike Protein. Current Biology. 2020, 30 (11): 2196–2203.e3. ISSN 0960-9822. doi:10.1016/j.cub.2020.05.023.
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来源
- Peiris, Jsm; Lai, St; Poon, Llm; Guan, Y; Yam, Lyc; Lim, W; Nicholls, J; Yee, Wks; Yan, Ww. Coronavirus as a possible cause of severe acute respiratory syndrome. The Lancet. 2003-04, 361 (9366): 1319–1325 [2021-04-07]. PMC 7112372 . PMID 12711465. doi:10.1016/S0140-6736(03)13077-2. （原始内容存档于2021-05-25） （英语）.
- Rota, P. A. Characterization of a Novel Coronavirus Associated with Severe Acute Respiratory Syndrome. Science. 2003-05-30, 300 (5624): 1394–1399. Bibcode:2003Sci...300.1394R. PMID 12730500. doi:10.1126/science.1085952.
- Marra, Marco A.; Jones, Steven J. M.; Astell, Caroline R.; Holt, Robert A.; Brooks-Wilson, Angela; Butterfield, Yaron S. N.; Khattra, Jaswinder; Asano, Jennifer K.; Barber, Sarah A. The Genome Sequence of the SARS-Associated Coronavirus. Science. 2003-05-30, 300 (5624): 1399–1404 [2021-04-07]. Bibcode:2003Sci...300.1399M. ISSN 0036-8075. PMID 12730501. doi:10.1126/science.1085953. （原始内容存档于2021-03-20） （英语）.
- Snijder, Eric J.; Bredenbeek, Peter J.; Dobbe, Jessika C.; Thiel, Volker; Ziebuhr, John; Poon, Leo L.M.; Guan, Yi; Rozanov, Mikhail; Spaan, Willy J.M. Unique and Conserved Features of Genome and Proteome of SARS-coronavirus, an Early Split-off From the Coronavirus Group 2 Lineage. Journal of Molecular Biology. 2003-08, 331 (5): 991–1004 [2021-04-07]. PMC 7159028 . PMID 12927536. doi:10.1016/S0022-2836(03)00865-9. （原始内容存档于2020-10-19） （英语）.
- Yount, B.; Roberts, R. S.; Lindesmith, L.; Baric, R. S. Rewiring the severe acute respiratory syndrome coronavirus (SARS-CoV) transcription circuit: Engineering a recombination-resistant genome. Proceedings of the National Academy of Sciences. 2006-08-15, 103 (33): 12546–12551 [2020-02-14]. Bibcode:2006PNAS..10312546Y. ISSN 0027-8424. PMC 1531645 . PMID 16891412. doi:10.1073/pnas.0605438103. （原始内容存档于2012-10-29） （英语）.
- Thiel V (编). Coronaviruses: Molecular and Cellular Biology 1st. Caister Academic Press. 2007. ISBN 978-1-904455-16-5.
- Enjuanes L, et al. Coronavirus Replication and Interaction with Host. Animal Viruses: Molecular Biology. Caister Academic Press. 2008. ISBN 978-1-904455-22-6.
外部連結
- WHO press release identifying and naming the SARS virus（页面存档备份，存于互联网档案馆）
- The SARS virus genetic map
- Science special on the SARS virus（页面存档备份，存于互联网档案馆） (free content: no registration required)
- McGill University SARS Resources. [2015-06-15]. （原始内容存档于2005-03-01）.
- U.S. Centers for Disease Control and Prevention (CDC) SARS home
- World Health Organization on alert（页面存档备份，存于互联网档案馆）
- SARS coronavirus. NCBI Taxonomy Browser. [2020-02-14]. 227859. （原始内容存档于2020-11-14）.
- Survival of Severe Acute Respiratory Syndrome Coronavirus（页面存档备份，存于互联网档案馆）
参见
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嚴重急性呼吸系統綜合症相關冠狀病毒 SARSr-CoV（Sarbevirus） | ||||||||||||||||||||||||||||||||||
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| SARSr-CoV |
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