猫冠状病毒

猫冠状病毒
病毒分類
（未分级）：	病毒 Virus
域：	核糖病毒域 Riboviria
界：	正核糖病毒界 Orthornavirae
门：	小核糖病毒门 Pisuviricota
纲：	小南嵌套病毒纲 Pisoniviricetes
目：	套式病毒目 Nidovirales
科：	冠状病毒科 Coronaviridae
属：	甲型冠狀病毒屬 Alphacoronavirus
种：	貓冠狀病毒 Alphacoronavirus 1
病毒：	猫冠状病毒 Feline coronavirus
毒株
	Feline coronavirus C1Je; Feline coronavirus type I; Feline coronavirus type II; Feline infectious peritonitis virus WSU 79-1146;

猫冠状病毒（Feline coronavirus、FCoV）是甲型冠狀病毒屬的一種病毒，是以猫为宿主的冠狀病毒，普遍存在於世界各地。90%以上的猫也带有冠状病毒^[2]。这种病毒属于甲型冠状病毒一型（Alphacoronavirus 1）^[3]，該物種除猫冠状病毒外還包括犬冠状病毒。猫冠状病毒又可分為兩型，一型是感染肠道的猫肠道冠状病毒（Feline enteric coronavirus、FECV），另一型是引起猫传染性腹膜炎的猫传染性腹膜炎病毒（Feline infectious peritonitis virus、FIPV）。

猫冠状病毒通常由健康的猫排泄在粪便中，并通过粪口途径传播给其他猫^[4]。在有多只猫的环境中，这种病毒的传播速率远远高于单只猫的环境^[2]。FECV通常不會造成嚴重症狀，但其變異為FIPV後会导致猫传染性腹膜炎，对于这种疾病的治疗通常只有针对症状和缓和医疗，不過吉利德（Gilead）公司研發的GS-441524（瑞德西韋之前体药物）對此可能具有療效。^[5]

参考资料

^ ICTV 9th Report (2011) Coronaviridae. International Committee on Taxonomy of Viruses (ICTV). [10 January 2019]. （原始内容存档于2020-01-23）.
^ ^2.0 ^2.1 Taharaguchi, Satoshi; Soma, Takehisa; Hara, Motonobu. Prevalence of Feline Coronavirus Antibodies in Japanese Domestic Cats during the Past Decade. Journal of Veterinary Medical Science. 2012, 74 (10): 1355–8. PMID 22673084. doi:10.1292/jvms.11-0577.
^ John Antoniw. Members of Genus: Alphacoronavirus. [21 July 2013]. （原始内容存档于2015-09-23）.
^ Hartmann, Katrin. Feline infectious peritonitis. Veterinary Clinics of North America: Small Animal Practice. 2005, 35 (1): 39–79. PMID 15627627. doi:10.1016/j.cvsm.2004.10.011.
^ Pedersen, NC; Perron, M; Bannasch, M. Efficacy and safety of the nucleoside analog GS-441524 for treatment of cats with naturally occurring feline infectious peritonitis.. Journal of Feline Medicine and Surgery. 2019, 21 (4): 271–281. PMC 6435921 . PMID 30755068. doi:10.1177/1098612X19825701.

外部链接

[1] ICTV 9th Report (2011) Coronaviridae. International Committee on Taxonomy of Viruses (ICTV). [10 January 2019]. （原始内容存档于2020-01-23）.

[taharaguchi-2] 2.0 ^2.1 Taharaguchi, Satoshi; Soma, Takehisa; Hara, Motonobu. Prevalence of Feline Coronavirus Antibodies in Japanese Domestic Cats during the Past Decade. Journal of Veterinary Medical Science. 2012, 74 (10): 1355–8. PMID 22673084. doi:10.1292/jvms.11-0577.

[dpvweb-3] John Antoniw. Members of Genus: Alphacoronavirus. [21 July 2013]. （原始内容存档于2015-09-23）.

[4] Hartmann, Katrin. Feline infectious peritonitis. Veterinary Clinics of North America: Small Animal Practice. 2005, 35 (1): 39–79. PMID 15627627. doi:10.1016/j.cvsm.2004.10.011.

[pedersen-5] Pedersen, NC; Perron, M; Bannasch, M. Efficacy and safety of the nucleoside analog GS-441524 for treatment of cats with naturally occurring feline infectious peritonitis.. Journal of Feline Medicine and Surgery. 2019, 21 (4): 271–281. PMC 6435921 . PMID 30755068. doi:10.1177/1098612X19825701.

[1]

[2]

[3]

[4]

[5]