替利定

替利定
	(1S,2R)-tilidine (dextilidine; top),; (1R,2S)-tilidine (bottom); [skeletal diagram 2D]
	(1S,2R)-tilidine (dextilidine; top),; (1R,2S)-tilidine (bottom); [ball-and-stick diagram 3D]
臨床資料
商品名（英語：Drug nomenclature）	Valoron, others
其他名稱	Tilidate (BAN UK)
AHFS/Drugs.com	國際藥品名稱
給藥途徑	By mouth, rectal, intramuscular, intravenous
藥物類別（英語：Drug class）	Opioid
ATC碼	N02AX01 (WHO) ;
法律規範狀態
法律規範	澳：受管控（S8）; 加：Schedule I; 德：Prescription only (Anlage III for higher doses) if combined with naloxone; 美：附表I;
藥物動力學數據
生物利用度	6% (parent compound), 99% (active metabolite)
藥物代謝	Metabolized by the liver, mostly via the enzymes CYP3A4 and CYP2C19
藥效起始時間（英語：Onset of action）	10–15 minutes
生物半衰期	3–5 hours
作用時間	4–6 hours
排泄途徑	Urine (90%)
識別資訊
	IUPAC命名法 Ethyl (1R,2S)-rel-2-(dimethylamino)-1-phenylcyclohex-3-ene-1-carboxylate; ;
CAS號	51931-66-9
DrugBank	DB13787;
UNII	GY33N31E9Y;
KEGG	D08597 ;
ChEBI	CHEBI:77823 ;
ChEMBL	ChEMBL563449 ;
ECHA InfoCard	100.039.779
化學資訊
化學式	C17H23NO2
摩爾質量	273.38 g·mol−1
3D模型（JSmol（英語：JSmol））	交互式圖像;
	SMILES O=C(OCC)[C@@]1(CCC=C[C@H]1N(C)C)C2=CC=CC=C2;

替利定（英語：Tilidine，商品名：Valoron等）是一種含氮有機化合物，化學式為C₁₇H₂₃NO₂，屬於類阿片鎮痛藥，用於中度至重度疼痛^[4]^[5]。

參考文獻

^ Vollmer KO, Thomann P, Hengy H. Pharmacokinetics of tilidine and metabolites in man. Arzneimittel-Forschung. October 1989, 39 (10): 1283–8. PMID 2610722.
^ ^2.0 ^2.1 ^2.2 Tilidin N Sandoz® DP Lösung zum Einnehmen [Tilidin N Sandoz ® DP oral solution] (PDF). Wooden Churches: Sandoz Pharmaceuticals GmbH. December 2012 [18 April 2014]. （原始內容 (PDF)存檔於2 May 2014）（德語）.
^ Anvisa. RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial [Collegiate Board Resolution No. 784 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control]. Diário Oficial da União. 2023-03-31 (2023-04-04) [2023-08-16]. （原始內容存檔於2023-08-03）（巴西葡萄牙語）.
^ Brayfield A (編). Tilidine Hydrochloride. Martindale: The Complete Drug Reference. Pharmaceutical Press. 13 December 2013 [18 April 2014].
^ Tilidine. Drugs.com. [8 February 2020] （英語）.