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萘咪酮

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萘咪酮
識別資訊
CAS號64212-22-2  checkY
PubChem CID
ChemSpider
UNII
CompTox Dashboard英語CompTox Chemicals Dashboard (EPA)
化學資訊
化學式C15H12N2O
摩爾質量236.27 g·mol−1
3D模型(JSmol英語JSmol
  • C1=CC=C2C=C(C=CC2=C1)C(=O)CN3C=CN=C3
  • InChI=1S/C15H12N2O/c18-15(10-17-8-7-16-11-17)14-6-5-12-3-1-2-4-13(12)9-14/h1-9,11H,10H2 ☒N
  • Key:ITPVLJQRUQVNSD-UHFFFAOYSA-N ☒N

萘咪酮(英語:Nafimidone)是一種咪唑抗驚厥藥英語anticonvulsant,分子式C15H12N2O,帶有一個基團,在尋找抗真菌藥的研究中意外發現。

合成

萘咪酮的合成[1][2]

參考文獻

  1. ^ Tajana A, Portioli F, Subissi A, Nardi D. [N-Naphthacylimidazoles and N-((beta-naphthyl-beta-hydroxy)ethyl) imidazoles with anticonvulsant activity]. Bollettino Chimico Farmaceutico. March 1981, 120 (3): 185–90. PMID 7272022. 
  2. ^ Walker KA, Wallach MB, Hirschfeld DR. 1-(Naphthylalkyl)-1H-imidazole derivatives, a new class of anticonvulsant agents. Journal of Medicinal Chemistry. January 1981, 24 (1): 67–74. PMID 7205879. doi:10.1021/jm00133a015. 

外部連結