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萘咪酮

维基百科,自由的百科全书
萘咪酮
识别信息
CAS号64212-22-2  checkY
PubChem CID
ChemSpider
UNII
CompTox Dashboard英语CompTox Chemicals Dashboard (EPA)
化学信息
化学式C15H12N2O
摩尔质量236.27 g·mol−1
3D模型(JSmol英语JSmol
  • C1=CC=C2C=C(C=CC2=C1)C(=O)CN3C=CN=C3
  • InChI=1S/C15H12N2O/c18-15(10-17-8-7-16-11-17)14-6-5-12-3-1-2-4-13(12)9-14/h1-9,11H,10H2 ☒N
  • Key:ITPVLJQRUQVNSD-UHFFFAOYSA-N ☒N

萘咪酮(英语:Nafimidone)是一种咪唑抗惊厥药英语anticonvulsant,分子式C15H12N2O,带有一个基团,在寻找抗真菌药的研究中意外发现。

合成

萘咪酮的合成[1][2]

参考文献

  1. ^ Tajana A, Portioli F, Subissi A, Nardi D. [N-Naphthacylimidazoles and N-((beta-naphthyl-beta-hydroxy)ethyl) imidazoles with anticonvulsant activity]. Bollettino Chimico Farmaceutico. March 1981, 120 (3): 185–90. PMID 7272022. 
  2. ^ Walker KA, Wallach MB, Hirschfeld DR. 1-(Naphthylalkyl)-1H-imidazole derivatives, a new class of anticonvulsant agents. Journal of Medicinal Chemistry. January 1981, 24 (1): 67–74. PMID 7205879. doi:10.1021/jm00133a015. 

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