補體成分6

補體成分6
已知的結構
PDB	直系同源搜索: PDBe RCSB
PDBID列表
	3T5O、4A5W、4E0S
識別號
別名	C6；, complement C6
外部ID	OMIM：217050 MGI：88233 HomoloGene：47 GeneCards：C6
相關疾病
	complement component 9 deficiency
基因位置（人類）
染色體	5號染色體
終止	41,261,438 bp
基因位置（小鼠）
染色體	小鼠15號染色體
終止	4,844,449 bp
基因本體
分子功能	• 血漿蛋白結合;
細胞組分	• 細胞外區域; • 外排體; • 補體系統膜攻擊複合物;
生物學過程	• positive regulation of activation of membrane attack complex; • immune system process; • complement activation; • in utero embryonic development; • 細胞溶解; • regulation of complement activation; • 免疫反應; • positive regulation of angiogenesis; • 經典途徑; • positive regulation of complement activation; • 先天免疫系統;
	Sources:Amigo / QuickGO
直系同源
	729
	12274
	ENSG00000039537
	ENSMUSG00000022181
	P13671
	無數據
	NM_000065; NM_001115131
	NM_016704
	NP_000056; NP_001108603
	無數據
	維基數據
檢視/編輯人類	檢視/編輯小鼠

補體成分C6（Complement component 6），在人體內是一個由C6基因編碼的蛋白質，是補體系統的一部分，功能是形成膜攻擊複合物（MAC）。C6缺陷的患者更易被細菌感染^[6]^[7]^:41-45。

參考

^ 與補體成分6相關的疾病；在維基數據上查看/編輯參考.
^ ^2.0 ^2.1 ^2.2 GRCh38: Ensembl release 89: ENSG00000039537 - Ensembl, May 2017
^ ^3.0 ^3.1 ^3.2 GRCm38: Ensembl release 89: ENSMUSG00000022181 - Ensembl, May 2017
^ Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Entrez Gene: complement component 6.
^ 曹雪濤等. 醫學免疫學第6版. 北京: 人民衛生出版社. 2013. ISBN 978-7-117-17101-4.

拓展閱讀

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外部連結

醫學主題詞表（MeSH）：Complement+C6

這是一篇與生物化學相關的小作品。您可以透過編輯或修訂擴充其內容。

[1] 與補體成分6相關的疾病；在維基數據上查看/編輯參考.

[refGRCh38Ensembl-2] 2.0 ^2.1 ^2.2 GRCh38: Ensembl release 89: ENSG00000039537 - Ensembl, May 2017

[refGRCm38Ensembl-3] 3.0 ^3.1 ^3.2 GRCm38: Ensembl release 89: ENSMUSG00000022181 - Ensembl, May 2017

[4] Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.

[5] Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-6] Entrez Gene: complement component 6.

[7] 曹雪濤等. 醫學免疫學第6版. 北京: 人民衛生出版社. 2013. ISBN 978-7-117-17101-4.

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