細胞黏附
 | 此條目可參照英語維基百科相應條目來擴充。 |
細胞黏附是指細胞透過表面的特殊分子，和鄰近細胞或細胞外基質相互作用並且結合的過程。此過程可以透過兩個細胞的直接接觸（例如細胞連接），也可以間接地由細胞附著在細胞外基質上來達成。細胞外基質是細胞所釋出的物質，可以填滿細胞周圍的空間[1]。細胞黏附主要是由細胞表面細胞黏附分子（CAM，一種跨膜蛋白）所介導[2]。細胞黏附會連接各細胞，且參與細胞的信號傳導，使細胞能夠感知並回應周圍環境的變化[1][3]。細胞黏附在多細胞生物的組織形成、細胞遷移等過程中扮演重要角色[4]。細胞黏附的異常與多種疾病（如癌症[5][6]及關節炎[7]）密切相關，同時也影響感染原（細菌或病毒）的疾病傳播[8][9]。
相關條目
參考資料
- ^ 1.0 1.1 Alberts, Bruce; Johnson, Alexander; Lewis, Julian; Morgan, David; Raff, Martin; Roberts, Keith; Walter, Peter. Molecular Biology of the Cell. 6th. Garland Science. 2014. ISBN 9780815344322.
- ^ Lodish, Harvey; Berk, Arnold; Matsudaira, Paul; Kaiser, Chris A.; Krieger, Monty; Scott, Matthew P.; Zipursky, Lawrence; Darnell, James. Molecular Cell Biology 5th. W.H. Freeman. 2003. ISBN 978-0716743668.
- ^ Gumbiner, Barry M. Cell Adhesion: The Molecular Basis of Tissue Architecture and Morphogenesis. Cell. 1996, 84 (3): 345–357. PMID 8608588. S2CID 13443584. doi:10.1016/S0092-8674(00)81279-9
.
- ^ Sumigray, Kaelyn D.; Lechler, Terry. Cell Adhesion in Epidermal Development and Barrier Formation 112. 2015: 383–414. ISBN 9780124077584. PMC 4737682 . PMID 25733147. doi:10.1016/bs.ctdb.2014.11.027.
|journal=被忽略 (幫助) - ^ Okegawa, T; Pong, RC; Li, Y; Hsieh, JT. The role of cell adhesion molecule in cancer progression and its application in cancer therapy.. Acta Biochimica Polonica. 2004, 51 (2): 445–57. PMID 15218541. doi:10.18388/abp.2004_3583 .
- ^ Hirohashi, Setsuo; Kanai, Yae. Cell adhesion system and human cancer morphogenesis. Cancer Science. 2003, 94 (7): 575–581. PMC 11160151 . PMID 12841864. S2CID 22154824. doi:10.1111/j.1349-7006.2003.tb01485.x .
- ^ Szekanecz, Zoltan; Koch, Alisa E. Cell–cell interactions in synovitis: Endothelial cells and immune cell migration. Arthritis Research. 2000, 2 (5): 368–373. PMC 130138 . PMID 11094450. doi:10.1186/ar114 .
- ^ Pizarro-Cerdá, Javier; Cossart, Pascale. Bacterial Adhesion and Entry into Host Cells. Cell. 2006, 124 (4): 715–727. PMID 16497583. S2CID 5769387. doi:10.1016/j.cell.2006.02.012 .
- ^ Mateo, M.; Generous, A.; Sinn, P. L.; Cattaneo, R. Connections matter - how viruses use cellcell adhesion components. Journal of Cell Science. 2015, 128 (3): 431–439. PMC 4311127 . PMID 26046138. doi:10.1242/jcs.159400.
外部連結
- The Cell by G. Cooper (online textbook)
- Molecular Cell Biology by Lodish et al. (online textbook)
- Molecular Biology of the Cell by Alberts et al. (online textbook)
- Cell Adhesion and Extracellular Matrix - The Virtual Library of Biochemistry, Molecular Biology and Cell Biology
