SH3结构域 （英语：SH3 domain ，全称Src同源3结构域 ，英语：SRC Homology 3 Domain ）是最早在病毒 接头蛋白 v-Crk及酪氨酸激酶 Src 、Abl 中发现的长约60个氨基酸 残基的保守 结构域 [ 1] [ 2] 磷酸肌醇3-激酶 、Ras超家族 G蛋白 、cdc25 中也存在[ 3] [ 4] [ 5]
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