SR-16435

SR-16435
识别信息
	IUPAC命名法 1-[1-(9-bicyclo[3.3.1]nonanyl)piperidin-4-yl]-3H-indol-2-one; ;
CAS号	857262-16-9
PubChem CID	11461888;
化学信息
化学式	C22H30N2O
摩尔质量	338.50 g·mol−1
3D模型（JSmol（英语：JSmol））	交互式图像;
	SMILES C1CC2CCCC(C1)C2N3CCC(CC3)N4C(=O)CC5=CC=CC=C54;
	InChI InChI=1S/C22H30N2O/c25-21-15-18-5-1-2-10-20(18)24(21)19-11-13-23(14-12-19)22-16-6-3-7-17(22)9-4-8-16/h1-2,5,10,16-17,19,22H,3-4,6-9,11-15H2; Key:XVFXJQGBDPFCRF-UHFFFAOYSA-N;

参考文献

^ Khroyan TV, Zaveri NT, Polgar WE, Orduna J, Olsen C, Jiang F, Toll L. SR 16435 [1-(1-(bicyclo[3.3.1]nonan-9-yl)piperidin-4-yl)indolin-2-one], a novel mixed nociceptin/orphanin FQ/mu-opioid receptor partial agonist: analgesic and rewarding properties in mice. The Journal of Pharmacology and Experimental Therapeutics. February 2007, 320 (2): 934–43. PMID 17132815. S2CID 2920534. doi:10.1124/jpet.106.111997.
^ Spagnolo B, Calo G, Polgar WE, Jiang F, Olsen CM, Berzetei-Gurske I, et al. Activities of mixed NOP and mu-opioid receptor ligands. British Journal of Pharmacology. February 2008, 153 (3): 609–19. PMC 2241792 . PMID 18059322. doi:10.1038/sj.bjp.0707598.
^ Sukhtankar DD, Zaveri NT, Husbands SM, Ko MC. Effects of spinally administered bifunctional nociceptin/orphanin FQ peptide receptor/μ-opioid receptor ligands in mouse models of neuropathic and inflammatory pain. The Journal of Pharmacology and Experimental Therapeutics. July 2013, 346 (1): 11–22. PMC 3684842 . PMID 23652222. doi:10.1124/jpet.113.203984.