6-羟基犬尿喹啉酸
6-羟基犬尿喹啉酸 | |
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IUPAC名 4,6-Dihydroxyquinoline-2-carboxylic acid | |
识别 | |
CAS号 | 3778-29-8 |
PubChem | 440752 |
ChemSpider | 389622 |
SMILES |
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InChI |
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InChIKey | CQUUHDQRJWXDPY-UHFFFAOYAS |
性质 | |
化学式 | C10H7NO4 |
摩尔质量 | 205.17 g·mol−1 |
若非注明,所有数据均出自标准状态(25 ℃,100 kPa)下。 |
6-羟基犬尿喹啉酸(英語:6-Hydroxykynurenic acid)是一种含氮杂环化合物,化学式为C10H7NO4,为犬尿喹啉酸(一种氨基酸代谢产物)的衍生物,存在于银杏中[1],能作为AMPA和NMDA的受体拮抗剂[2]。
参考文献
- ^ van Beek, Teris A. Chemical analysis of Ginkgo biloba leaves and extracts. Journal of Chromatography A. Chromatographic and Electrophoretic Analysis of Secondary Metabolites of Plants. 2002-08-16, 967 (1): 21–55. ISSN 0021-9673. PMID 12219929. doi:10.1016/S0021-9673(02)00172-3 (英语).
- ^ Weber, Marco; Dietrich, Dirk; Gräsel, Ines; Reuter, Gerhard; Seifert, Gerald; Steinhäuser, Christian. 6-Hydroxykynurenic acid and kynurenic acid differently antagonise AMPA and NMDA receptors in hippocampal neurones: 6-Hydroxykynurenate blocks glutamate receptors. Journal of Neurochemistry. 2001-12-20, 77 (4): 1108–1115. PMID 11359876. S2CID 23178914. doi:10.1046/j.1471-4159.2001.00340.x (英语).