豆甾烷醇
豆甾烷醇 | |
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IUPAC名 (3S,5S,8R,9S,10S,13R,14S,17R)-17-((2R,5R)-5-ethyl-6-methylheptan-2-yl)-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-3-ol | |
系统名 (1S,2S,5S,7S,10R,11S,14R,15R)-14-[(1R,4R)-4-ethyl-1,5-dimethylhexyl]-2,15-dimethyltetracyclo[8.7.0.02,7.011,15]heptadecan-5-ol (1S,2S,5S,7S,10R,11S,14R,15R)-2,15-二甲基-14-[(1R,4R)-1,5-二甲基-4-乙基己基]四环[8.7.0.02,7.011,15]-5-十七醇 | |
别名 | (3β)-Stigmastan-3-ol; (3β,5α)-Stigmastan-3-ol; β-Sitostanol; Dihydrositosterin; Dihydrositosterol; Dihydro-β-sitosterol; Fucostanol; Spinastanol; 24α-Ethylcholestanol |
识别 | |
CAS号 | 83-45-4 |
PubChem | 241572 |
ChemSpider | 13078158 |
SMILES |
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ChEBI | 89400 |
性质 | |
化学式 | C29H52O |
摩尔质量 | 416.72 g·mol−1 |
沸点 | 139.4 - 139.8 °C(273 K) |
若非注明,所有数据均出自标准状态(25 ℃,100 kPa)下。 |
豆甾烷醇(英語:Stigmastanol,或称为谷甾烷醇,sitostanol,豆甾烷-3β-醇,Stigmastan-3β-ol)是一种存在于许多植物中的植物固醇,这一类的化合物能抑制人体对食物中胆固醇的吸收[1][2][3]。动物实验表明豆甾烷醇还能抑制肝脏胆固醇的合成[1]
参考文献
- ^ 1.0 1.1 Batta, Ashok K.; Xu, Guorong; Honda, Akira; Miyazaki, Teruo; Salen, Gerald. Stigmasterol reduces plasma cholesterol levels and inhibits hepatic synthesis and intestinal absorption in the rat. Metabolism, Clinical and Experimental. 2006, 55 (3): 292–299. doi:10.1016/j.metabol.2005.08.024.
- ^ Heinemann T, Pietruck B, Kullak-Ublick G, von Bergmann K. Comparison of sitosterol and sitostanol on inhibition of intestinal cholesterol absorption. Agents and Actions. Supplements . 1988, 26: 117–122. PMID 3265272.
- ^ Heinemann T, Kullak-Ublick GA, Pietruck B, von Bergmann K. Mechanisms of action of plant sterols on inhibition of cholesterol absorption. Comparison of sitosterol and sitostanol. European Journal of Clinical Pharmacology . 1991, 40 (Suppl 1): S59–63. PMID 2044646. doi:10.1007/BF01409411.
- ^ Thomasson Crompton, David William; Nickol, Brent B. Biology of the Acanthocephala. Cambridge University Press. 1985: 185 [2019-10-15]. ISBN 9780521246743. (原始内容存档于2016-04-11).
- ^ Paxena, P. B. Chemistry of Alkaloids. Discovery Publishing Hous. 2007: 231 [2019-10-15]. ISBN 9788183563161. (原始内容存档于2016-04-12).
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