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半乳糖1-脱氢酶 (NADP+)

维基百科,自由的百科全书
半乳糖1-脱氢酶 (NADP+)
识别码
EC編號 1.1.1.120
CAS号 37250-51-4
数据库
IntEnz IntEnz浏览
BRENDA英语BRENDA BRENDA入口
ExPASy英语ExPASy NiceZyme浏览
KEGG KEGG入口
MetaCyc英语MetaCyc 代谢路径
PRIAM英语PRIAM_enzyme-specific_profiles 概述
PDB RCSB PDB PDBj PDBe PDBsum
基因本体 AmiGO / EGO

半乳糖1-脱氢酶 (NADP+)(英語:galactose 1-dehydrogenase (NADP+)EC 1.1.1.120页面存档备份,存于互联网档案馆)),是一种以NAD+NADP+受体、作用于供体CH-OH基团上的氧化还原酶。这种催化以下酶促反应

D-半乳糖 + NADP+ D-半乳糖酸内酯 + NADPH + H+

半乳糖1-脱氢酶 (NADP+)也能催化L-阿拉伯糖、6-脱氧-D-半乳糖以及2-脱氧-D-半乳糖等发生反应。

参考文献

  • Cline AL, Hu AS. The isolation of three sugar dehydrogenases from a psuedomonad原文如此. J. Biol. Chem. 1965, 240 (11): 4488–92. PMID 5845847. 
  • Cline AL, Hu AS. Enzymatic characterization and comparison of three sugar dehydrogenases from a pseudomonad. J. Biol. Chem. 1965, 240 (11): 4493–7. PMID 5845848. 
  • Cline AL, Hu AS. Some physical properties of three sugar dehydrogenases from a pseudomonad. J. Biol. Chem. 1965, 240 (11): 4498–502. PMID 5845849. 
  • Schiwara HW, Domagk GF. Degradation of deoxysurgars by bacterial enzymes. V. Purification and characterization of an NADP-dependent abequose dehydrogenase from Pseudomonas putida. Hoppe. Seylers. Z. Physiol. Chem. 1968, 349 (10): 1321–9. PMID 4387016.