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Electrochemotherapy is a therapeutic approach providing delivery into cell interior of non-permenant drugs with intracellular targets. It is based on the local application of short and intense electric pulses that transiently permeabilized cell membrane, thus allowing transport of molecules otherwise not permitted by a cellular membrane ^[1]^[2]

References

^ Mir LM, Orlowski S, Belehradek J, Paoletti C (1991). "Electrochemotherapy potentiation of antitumour effect of bleomycin by local electric pulses". Eur. J. Cancer 27 (1): 68–72. PMID 1707289.
^ Sersa G, Cemazar M, Miklavcic D (August 1995). "Antitumor effectiveness of electrochemotherapy with cis-diamminedichloroplatinum(II) in mice". Cancer Res. 55 (15): 3450–5. PMID 7614485.

[1] Mir LM, Orlowski S, Belehradek J, Paoletti C (1991). "Electrochemotherapy potentiation of antitumour effect of bleomycin by local electric pulses". Eur. J. Cancer 27 (1): 68–72. PMID 1707289.

[2] Sersa G, Cemazar M, Miklavcic D (August 1995). "Antitumor effectiveness of electrochemotherapy with cis-diamminedichloroplatinum(II) in mice". Cancer Res. 55 (15): 3450–5. PMID 7614485.

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