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異丹葉大黃素

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異丹葉大黃素
Chemical structure of isorhapontigenin.
IUPAC名
5-[(E)-2-(4-Hydroxy-3-methoxyphenyl)ethen-1-yl]benzene-1,3-diol
別名 3,4',5-trihydroxy-3'-methoxystilbene
ISO
識別
CAS號 32507-66-7
20767-15-1((non-specific))  checkY
PubChem 5318650
ChemSpider 4477172
SMILES
 
  • COC1=C(C=CC(=C1)C=CC2=CC(=CC(=C2)O)O)O
InChI
 
  • 1/C15H14O4/c1-19-15-8-10(4-5-14(15)18)2-3-11-6-12(16)9-13(17)7-11/h2-9,16-18H,1H3/b3-2+
InChIKey ANNNBEZJTNCXHY-NSCUHMNNBY
性質
化學式 C15H14O4
莫耳質量 258.27 g/mol g·mol⁻¹
若非註明,所有數據均出自標準狀態(25 ℃,100 kPa)下。

異丹葉大黃素(英語:Isorhapontigenin,簡稱ISO)是一種芪類有機化合物,分子式C15H14O4,與丹葉大黃素的區別在於甲氧基羥基的位置相反[1],存在於傳統中藥閉苞買麻藤(學名:Gnetum cleistostachyum)中[2]

參考文獻

  1. ^ Li, H.; Wang, A.; Huang, Y.; Liu, D.; Wei, C.; Williams, G.; Zhang, C.; Liu, G.; Liu, Y.; Hao, D.; Hui, R. T.; Lin, M.; Liang, C. C. Isorhapontigenin, a new resveratrol analog, attenuates cardiac hypertrophy via blocking signaling transduction pathways. Free Radical Biology and Medicine. 2005, 38 (2): 243–257. PMID 15607907. doi:10.1016/j.freeradbiomed.2004.10.020. 
  2. ^ Fang, Y.; Yu, Y.; Hou, Q.; Zheng, X.; Zhang, M.; Zhang, D.; Li, J.; Wu, X. -R.; Huang, C. The Chinese Herb Isolate Isorhapontigenin Induces Apoptosis in Human Cancer Cells by Down-regulating Overexpression of Antiapoptotic Protein XIAP. Journal of Biological Chemistry. 2012, 287 (42): 35234–35243. PMC 3471739可免費查閱. PMID 22896709. doi:10.1074/jbc.M112.389494可免費查閱.