原兒茶酸乙酯
| 原兒茶酸乙酯[1] | |
|---|---|
| |
| IUPAC名 Ethyl 3,4-dihydroxybenzoate | |
| 別名 | 3,4-二羥基苯甲酸乙酯 EDHB |
| 識別 | |
| CAS號 | 3943-89-3 
|
| PubChem | 77547 |
| ChemSpider | 69954 |
| SMILES |
|
| InChI |
|
| InChIKey | KBPUBCVJHFXPOC-UHFFFAOYSA-N |
| EINECS | 223-529-0 |
| ChEBI | 132364 |
| 性質 | |
| 化學式 | C9H10O4 |
| 摩爾質量 | 182.17 g·mol−1 |
| 外觀 | 白色或淡棕黃色晶體 |
| 氣味 | 無臭或微弱的苯酚氣味 |
| 熔點 | 132-135 °C（405-408 K） |
| 沸點 | 357-358 °C（630-631 K）（[2]） |
| 溶解性（水） | 不溶於水，可溶於乙醇 |
| 若非註明，所有數據均出自標準狀態（25 ℃，100 kPa）下。 | |
原兒茶酸乙酯（英語：Ethyl protocatechuate）是原兒茶酸與乙醇形成的酯，分子式C9H10O4，可在花生的種皮中發現[3][4]，在葡萄酒中也有發現[5]。
原兒茶酸乙酯也是脯氨酸-4-羥化酶的抑制劑[6]，可用於保護心肌[7]。
參考文獻
- ^ Ethyl protocatechuate on FAO website[失效連結]
- ^ Ethyl protocatechuate on www.thegoodscentscompany.com
- ^ Huang, S. C.; Yen, G. C.; Chang, L. W.; Yen, W. J.; Duh, P. D. Identification of an Antioxidant, Ethyl Protocatechuate, in Peanut Seed Testa. Journal of Agricultural and Food Chemistry. 2003, 51 (8): 2380–2383. PMID 12670184. doi:10.1021/jf0210019.
- ^ Yen, W. J.; Chang, L. W.; Duh, P. D. Antioxidant activity of peanut seed testa and its antioxidative component, ethyl protocatechuate. LWT - Food Science and Technology. 2005, 38 (3): 193. doi:10.1016/j.lwt.2004.06.004.
- ^ Baderschneider, B.; Winterhalter, P. Isolation and Characterization of Novel Benzoates, Cinnamates, Flavonoids, and Lignans from Riesling Wine and Screening for Antioxidant Activity. Journal of Agricultural and Food Chemistry. 2001, 49 (6): 2788–2798. PMID 11409967. doi:10.1021/jf010396d.
- ^ Wang, J.; Buss, J. L.; Chen, G.; Ponka, P.; Pantopoulos, K. The prolyl 4-hydroxylase inhibitor ethyl-3,4-dihydroxybenzoate generates effective iron deficiency in cultured cells. FEBS Letters. 2002, 529 (2–3): 309–312. PMID 12372619. doi:10.1016/S0014-5793(02)03389-6.
- ^ Philipp, S.; Cui, L.; Ludolph, B.; Kelm, M.; Schulz, R.; Cohen, M. V.; Downey, J. M. Desferoxamine and ethyl-3,4-dihydroxybenzoate protect myocardium by activating NOS and generating mitochondrial ROS. AJP: Heart and Circulatory Physiology. 2005, 290 (1): H450–H457. PMID 16155105. doi:10.1152/ajpheart.00472.2005.