半方酸

半方酸
	IUPAC名; 3-hydroxycyclobut-3-ene-1,2-dione
別名	3-羥基環丁烯二酮; 串珠鐮刀菌素
識別
CAS號	31876-38-7
PubChem	40452
ChemSpider	36957
SMILES	O=C1C(\O)=C/C1=O;
InChI	1/C4H2O3/c5-2-1-3(6)4(2)7/h1,5H;
InChIKey	KGPQKNJSZNXOPV-UHFFFAOYAJ
性質
化學式	C4H2O3
摩爾質量	98.06 g·mol−1
熔點	158 °C
相關物質
相關化學品	方酸
	若非註明，所有數據均出自標準狀態（25 ℃，100 kPa）下。

半方酸是一種有機化合物，化學式為C₄H₂O₃，它在自然界以鈉鹽或鉀鹽的形式存在於鐮孢菌屬一些生物的次級代謝產物中。^[1]

它是在自然界中存在的最強的有機酸（pKa=0.88^[1]），水貂對其毒性最為敏感。^[2]

參考文獻

^ ^1.0 ^1.1 ^1.2 EFSA Panel on Contaminants in the Food Chain (CONTAM), Helle Katrine Knutsen, Jan Alexander, Lars Barregård, Margherita Bignami, Beat Brüschweiler, Sandra Ceccatelli, Bruce Cottrill, Michael Dinovi, Bettina Grasl‐Kraupp, Christer Hogstrand, Laurentius (Ron) Hoogenboom, Carlo Stefano Nebbia, Isabelle P Oswald, Annette Petersen, Martin Rose, Alain‐Claude Roudot, Tanja Schwerdtle, Christiane Vleminckx, Günter Vollmer, Heather Wallace, Sarah De Saeger, Gunnar Sundstøl Eriksen, Peter Farmer, Jean‐Marc Fremy, Yun Yun Gong, Karsten Meyer, Hanspeter Naegeli, Dominique Parent‐Massin, Hans van Egmond, Andrea Altieri, Paolo Colombo, Mari Eskola, Mathijs van Manen, Lutz Edler. Risks to human and animal health related to the presence of moniliformin in food and feed. EFSA Journal. 2018-03, 16 (3) [2021-09-26]. PMC 7009678 . PMID 32625822. doi:10.2903/j.efsa.2018.5082.
^ Morgan MK, Fitzgerald SD, Rottinghaus GE, Bursian SJ and Aulerich RJ. 1999. Toxic effects to mink of moniliformin extracted from Fusarium fujikuroi culture material. Veterinary and Human Toxicology 1 (1): pp 1-5