模板:PBB/54106

Toll-like receptor 9
标识
代号	TLR9; CD289
扩展标识	遗传学：605474 鼠基因：1932389 同源基因：68126 ChEMBL: 5804 GeneCards: TLR9 Gene
基因本体论描述 分子功能 · transmembrane signaling receptor activity · interleukin-1 receptor binding · siRNA binding 细胞成分 · Golgi membrane · extracellular region · cytoplasm · lysosome · endosome · endoplasmic reticulum · endoplasmic reticulum membrane · plasma membrane · endosome membrane · integral component of membrane · basolateral plasma membrane · apical plasma membrane · early phagosome · endolysosome membrane 生物过程 · toll-like receptor signaling pathway · response to molecule of bacterial origin · MyD88-dependent toll-like receptor signaling pathway · inflammatory response · I-kappaB phosphorylation · insulin receptor signaling pathway · positive regulation of gene expression · maintenance of gastrointestinal epithelium · negative regulation of NF-kappaB transcription factor activity · tumor necrosis factor production · negative regulation of interleukin-6 production · negative regulation of interleukin-8 production · positive regulation of chemokine production · positive regulation of granulocyte macrophage colony-stimulating factor production · positive regulation of interferon-beta production · positive regulation of interleukin-10 production · positive regulation of interleukin-12 production · positive regulation of interleukin-18 production · positive regulation of interleukin-6 production · positive regulation of interleukin-8 production · positive regulation of tumor necrosis factor production · negative regulation of toll-like receptor signaling pathway · positive regulation of toll-like receptor signaling pathway · toll-like receptor 9 signaling pathway · positive regulation of NF-kappaB import into nucleus · defense response to bacterium · positive regulation of I-kappaB kinase/NF-kappaB signaling · positive regulation of JUN kinase activity · positive regulation of interferon-gamma biosynthetic process · innate immune response · positive regulation of interferon-alpha biosynthetic process · positive regulation of interferon-beta biosynthetic process · positive regulation of transcription from RNA polymerase II promoter · positive regulation of JNK cascade · regulation of cytokine secretion · positive regulation of inflammatory response · defense response to Gram-negative bacterium · positive regulation of NF-kappaB transcription factor activity · positive regulation of nitric-oxide synthase biosynthetic process · negative regulation of calcium-transporting ATPase activity Sources: Amigo / QuickGO
直系同源体
物种	人类	小鼠
Entrez	54106	81897
Ensembl	ENSG00000239732	ENSMUSG00000045322
UniProt	Q9NR96	Q9EQU3
mRNA序列	NM_017442	NM_031178
蛋白序列	NP_059138	NP_112455
基因位置	Chr 3: 52.22 – 52.23 Mb	Chr 9: 106.22 – 106.23 Mb
PubMed查询	[1]	[2]