胱天蛋白酶4
胱天蛋白酶4(英语:Caspase 4)是一种在人类中由CASP4基因编码的酶。该酶属于胱天蛋白酶(Caspase)家族的成员。该酶是一种在天冬氨酸残基(LEVD-)处以蛋白水解方式裂解其他蛋白质的酶,其余的功能尚未完全了解,但据信它是一种炎症性胱天蛋白酶,与胱天蛋白酶1、5(以及鼠同源物胱天蛋白酶11)一起在免疫系统中发挥作用。[6]
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参考文献
- ^ 對胱天蛋白酶4起作用的藥物;在維基數據上查看/編輯參考.
- ^ 2.0 2.1 2.2 GRCh38: Ensembl release 89: ENSG00000196954 - Ensembl, May 2017
- ^ 3.0 3.1 3.2 GRCm38: Ensembl release 89: ENSMUSG00000033538 - Ensembl, May 2017
- ^ Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Martinon F, Tschopp J. Inflammatory caspases and inflammasomes: master switches of inflammation. Cell Death Differ. 2007, 14 (1): 10–22. PMID 16977329. doi:10.1038/sj.cdd.4402038 .
- ^ Smith C, Soti S, Jones Torey A, Nakagawa A, Xue D, and Yin H. NSAIDs are Caspase Inhibitors. Cell Chem Biol. 2017, 24 (3): 281–292. PMC 5357154 . PMID 28238723. doi:10.1016/j.chembiol.2017.02.003 .