吡啶-2-甲酸铬
吡啶-2-甲酸铬 | |||
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IUPAC名 Tris(picolinate)chromium(III) | |||
别名 | 2-吡啶甲酸铬 2-吡啶羧酸铬 吡啶-2-羧酸铬 | ||
识别 | |||
CAS号 | 14639-25-9 | ||
PubChem | 151932 | ||
ChemSpider | 133913 | ||
SMILES |
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InChI |
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InChIKey | CBDQOLKNTOMMTL-DFZHHIFOAM | ||
ChEBI | 50369 | ||
性质 | |||
化学式 | Cr(C6H4NO2)3 | ||
摩尔质量 | 418.33 g/mol g·mol⁻¹ | ||
若非注明,所有数据均出自标准状态(25 ℃,100 kPa)下。 |
吡啶-2-甲酸铬(简写:CrPic3)是一种化合物,用作营养补充剂以治疗2型糖尿病,以及促进减肥。[1] 它是红粉色的化合物,最初于1917年报道。[2][3]它难溶于水,在中性pH下的水中,溶解度为600 µmol/L。[4]它和其它三价铬化合物类似,化学性质上具有惰性,即在一般条件下稳定,它仅在较高温度下分解。[5]在较低的pH下,该配合物会游离出吡啶-2-甲酸和Cr3+离子。[4]
参考文献
- ^ Preuss, H. G.; Echard, B.; Perricone, N. V.; Bagchi, D.; Yasmin, T.; Stohs, S. J. Comparing metabolic effects of six different commercial trivalent chromium compounds. Journal of Inorganic Biochemistry. 2008, 102 (11): 1986–1990. PMID 18774175. doi:10.1016/j.jinorgbio.2008.07.012.
- ^ Vincent, John (2010). "Chromium: celebrating 50 years as an essential element?". Dalton Transactions. Royal Society of Chemistry. 39: 3787–3794. doi:10.1039/B920480F. PMID 20372701. Retrieved 20 March 2015.
- ^ Vincent, John. The Bioinorganic Chemistry of Chromium (III). Polyhedron (Elsevier B.V). 2001, 20: 1–26 [20 March 2015]. doi:10.1016/S0277-5387(00)00624-0. (原始内容存档于2015-09-24).
- ^ 4.0 4.1 Feng, Weiyue (2007). "Chapter 6—The Transport of chromium (III) in the body: Implications for Function". In Vincent, John. The Nutritional Biochemistry of Chromium (III) (PDF). Amsterdam: Elsevier B.V. pp. 121–137. ISBN 978-0-444-53071-4. Retrieved 20 March 2015.
- ^ Abou–Gamra, Zeinab; Abdel–Messih, Michel. Correlation of thermal and spectral properties of chromium(III) picolinate complex and kinetic study of its thermal degradation. Journal of Thermal Analysis and Calorimetry (Springer Netherlands). 2014, 117 (2): 993–1000 [1 April 2015]. doi:10.1007/s10973-014-3768-5. (原始内容存档于2019-07-30).