苏糖核酸
苏糖核酸(英语:Threose nucleic acid,缩写:TNA)是一种与DNA和RNA相似的化学物质,但组成物有所不同。地球上已知生物并未发现体内有此物质。
TNA的骨架是由重复排列的苏糖(threose)单位,经由磷酸酯键连结而成。在实验室中,可利用DNA聚合酶合成出DNA与TNA的混合长链。
外部链接
- Was simple TNA the first nucleic acid on Earth to carry a genetic code? (页面存档备份,存于互联网档案馆) - New scientist
- ORIGIN OF LIFE: A Simpler Nucleic Acid (页面存档备份,存于互联网档案馆) - Leslie Orgel
参考文献
- Orgel, Leslie. A Simpler Nucleic Acid. Science. Nov 2000, 290 (5495): 1306 – 1307. doi:10.1126/science.290.5495.1306.
- Watt, Gregory. Modified nucleic acids on display. Nature Chemical Biology. Feb 2005 [2007-07-25]. doi:10.1038/nchembio005. (原始内容存档于2016-03-08).
- Schoning, K; Scholz P; Guntha S; Wu X; Krishnamurthy R; Eschenmoser A. Chemical etiology of nucleic acid structure: the alpha-threofuranosyl-(3'->2') oligonucleotide system.. Science. Nov 2000. PMID 11082060.