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BSPP

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BSPP
臨床資料
ATC碼
  • 未分配
識別資訊
  • 2,6-di-tert-butyl-4-{[1-(hydroxymethyl)cyclopentyl]methyl}phenol
CAS號938174-18-6  checkY
PubChem CID
ChemSpider
CompTox Dashboard英語CompTox Chemicals Dashboard (EPA)
化學資訊
化學式C21H34O2
摩爾質量318.50 g·mol−1
3D模型(JSmol英語JSmol
  • C(C)(C)(C)C1=C(C(=CC(=C1)CC1(CCCC1)CO)C(C)(C)C)O
  • InChI=1S/C21H34O2/c1-19(2,3)16-11-15(12-17(18(16)23)20(4,5)6)13-21(14-22)9-7-8-10-21/h11-12,22-23H,7-10,13-14H2,1-6H3 checkY
  • Key:CTFKOMUXSHQLLL-UHFFFAOYSA-N checkY

BSPP(化學名: 2,6-二叔丁基-4-(3-羥基-2-螺戊基丙基)-苯酚2,6-di-tert-butyl-4-(3-hydroxy-2-spiropentylpropyl)-phenol)是一種有機化合物,是GABAB受體的正向別構調節劑,其作用效果和CGP7930BHFF類似。[1][2]

參考文獻 

  1. ^ Kerr DI, Khalafy J, Ong J, Perkins MV, Prager RH, Puspawati NM, Rimaz M. Synthesis and biological activity of allosteric modulators of GABAB receptors, part 2. 3-(2, 6-bis-tert-butyl-4-hydroxyphenyl) propanols.. Australian Journal of Chemistry. September 2006, 59 (7): 457–62. doi:10.1071/CH06164. 
  2. ^ Parker DA, Marino V, Ong J, Puspawati NM, Prager RH. The CGP7930 analogue 2,6-di-tert-butyl-4-(3-hydroxy-2-spiropentylpropyl)-phenol (BSPP) potentiates baclofen action at GABA(B) autoreceptors. Clinical and Experimental Pharmacology & Physiology. September 2008, 35 (9): 1113–5. PMID 18430050. doi:10.1111/j.1440-1681.2008.04948.x. 

外部連結