地諾帕明
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| 臨床資料 | |
|---|---|
| AHFS/Drugs.com | 國際藥品名稱 |
| 給藥途徑 | 口服（片劑） |
| ATC碼 |
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| 法律規範狀態 | |
| 法律規範 |
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| 識別資訊 | |
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| CAS號 | 71771-90-9 |
| PubChem CID | |
| IUPHAR/BPS | |
| ChemSpider | |
| UNII | |
| KEGG | |
| ChEMBL | |
| CompTox Dashboard (EPA) | |
| ECHA InfoCard | 100.163.233 |
| 化學資訊 | |
| 化學式 | C18H23NO4 |
| 摩爾質量 | 317.39 g·mol−1 |
| 3D模型（JSmol） | |
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地諾帕明（INN：denopamine）是一種強心藥，它可充當β1腎上腺素受體激動劑。[1]它用於治療心絞痛，[2]也可能在治療充血性心力衰竭[3] 和清除肺水腫方面具有潛在用途。[4]它在日本以商品名Kalgut（カルグート）上市，有5毫克和10毫克片劑以及5%細顆粒劑可供選擇。[5]
參考資料
- ^ Ishide T. Denopamine, a selective beta1-receptor agonist and a new coronary vasodilator. Current Medical Research and Opinion. 2002, 18 (7): 407–13. PMID 12487507. S2CID 25048757. doi:10.1185/030079902125001119.
- ^ Nakajima D, Negoro N, Nakaboh A, Nakakoji T, Hoshiga M, Nariyama J, et al. Effectiveness of low dose denopamine, a beta1-adrenoceptor agonist, in a patient with vasospastic angina refractory to intensive medical treatment. International Journal of Cardiology. April 2006, 108 (2): 281–3. PMID 15913812. doi:10.1016/j.ijcard.2005.03.012.
- ^ Nishio R, Matsumori A, Shioi T, Wang W, Yamada T, Ono K, Sasayama S. Denopamine, a beta1-adrenergic agonist, prolongs survival in a murine model of congestive heart failure induced by viral myocarditis: suppression of tumor necrosis factor-alpha production in the heart. Journal of the American College of Cardiology. September 1998, 32 (3): 808–15. PMID 9741531. doi:10.1016/S0735-1097(98)00314-3. hdl:2433/181223
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- ^ Sakuma T, Hida M, Nambu Y, Osanai K, Toga H, Takahashi K, et al. Beta1-adrenergic agonist is a potent stimulator of alveolar fluid clearance in hyperoxic rat lungs. Japanese Journal of Pharmacology. February 2001, 85 (2): 161–6. PMID 11286398. doi:10.1254/jjp.85.161 .
- ^ Kalgut (denopamine) Tablets 5, 10 mg; Fine granules 5%. Full Prescribing Information (PDF). Mitsubishi Tanabe Pharma Corporation. [6 March 2016]. （原始內容存檔 (PDF)於2024-03-31） （Japanese）.
