HIST4H4

HIST4H4
已知的結構 PDB 直系同源搜索: PDBe RCSB PDBID列表 4H9O、​3WKJ、​3AYW、​3WA9、​5B0Z、​5AVB、​2CV5、​5AV5、​3AV2、​3WTP、​3AV1、​3AZK、​3X1V、​5AV8、​1F66、​4QUU、​3CFS、​4YYK、​4QUT、​3NQJ、​3A6N、​3W99、​5AVC、​2RS9、​3F9Z、​3QZT、​3QBY、​3W97、​4M38、​4YM6、​3CFV、​4HGA、​1EQZ、​2RJE、​3QZV、​1HQ3、​4H9P、​3AZL、​3AFA、​1TZY、​3UVY、​5CPK、​3JPX、​4U9W、​4N3W、​4YYJ、​4YYD、​4H9N、​4H9R、​3AZI、​4LD9、​3UVX、​3AZH、​5BNX、​4N4F、​1U35、​4YYG、​3O36、​2ARO、​5AV9、​4H9S、​3AZF、​3W98、​4GQB、​4H9Q、​5BNV、​3WAA、​3AZG、​3AZE、​2RNY、​1ZKK、​2QQS、​2LVM、​3X1T、​3AN2、​2KWO、​3QZS、​3F9W、​5FFW、​5CPJ、​3F9X、​3IJ1、​4YM5、​3AZJ、​4YY6、​3AZN、​2IG0、​4YYH、​4YYI、​5CPI、​3W96、​3R45、​2KWN、​3F9Y、​5AV6、​3AZM、​5BO0、​3X1S、​4QYD、​4KGC、​3UVW、​4YYN、​3X1U、​3UW9、​2F8N、​3NQU、​5B0Y、​4YYM、​5C3I、​4Z5T、​5B24、​5FA5、​4Z2M、​5E5A、​5FWE、​5B2I、​5B40、​5B2J、​5JA4、​5AY8、​4ZUX
識別號
別名	H4-16；, H4/p, histone cluster 4, H4, histone cluster 4 H4, HIST4H4, H4 histone 16, H4C5, H4C4, H4C9, H4C12, H4C3, H4C13, H4C11, H4C1, H4C14, H4C15, H4C8, H4C6, H4C2, H4C16
外部ID	OMIM：615069 MGI：2448432 HomoloGene：134468 GeneCards：H4-16
基因位置（人類） 染色體 12號染色體 基因座 12p12.3 起始 14,767,999 bp 終止 14,771,131 bp
基因位置（小鼠） 染色體 小鼠13號染色體 基因座 13|13 A3.1 起始 22,224,806 bp 終止 22,225,532 bp
基因本體 分子功能 • protein domain specific binding • 血漿蛋白結合 • protein heterodimerization activity • DNA結合 • histone binding • RNA binding 細胞組分 • 膜 • 染色體 • 核質 • 細胞外區域 • nuclear chromosome • 核小體 • 外排體 • 細胞核 • 細胞外間質 • 大分子複合體 生物學過程 • telomere organization • epigenetic maintenance of chromatin in transcription-competent conformation • protein heterotetramerization • negative regulation of megakaryocyte differentiation • CENP-A containing chromatin assembly • DNA replication-dependent chromatin assembly • rDNA heterochromatin assembly • negative regulation of gene expression, epigenetic • DNA-templated transcription, initiation • double-strand break repair via nonhomologous end joining • beta-catenin-TCF complex assembly • telomere capping • nucleosome assembly • regulation of gene silencing by miRNA • regulation of megakaryocyte differentiation • regulation of hematopoietic stem cell differentiation Sources:Amigo / QuickGO
直系同源
物種	人類	小鼠
Entrez	121504	319158
Ensembl	ENSG00000197837	ENSMUSG00000060639
UniProt	P62805	P62806
mRNA​序列	NM_175054	NM_175656
蛋白序列	NP_003537 ​NP_003486 ​NP_003535 ​NP_003539 ​NP_003531 ​NP_003536	NP_291074 ​NP_783587 ​NP_783588 ​NP_835499 ​NP_835500 ​NP_001182350 ​NP_835515 ​NP_783585 ​NP_783586 ​NP_835582 ​NP_835583 ​NP_783583 ​NP_694813
基因位置​（UCSC）	Chr 12: 14.77 – 14.77 Mb	Chr 13: 22.22 – 22.23 Mb
PubMed​查找
維基數據
檢視/編輯人類 檢視/編輯小鼠

HIST4H4爲人體中的一種編碼一類組蛋白H4的基因。HIST4H4沒有內含子，編碼組蛋白H4家族中的一種蛋白質。HIST4H4基因對應的mRNA缺乏Poly(A)尾巴。不過，這類mRNA有一個回文終止元件。

拓展閱讀

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