DNA聚合酶δ
| DNA-directed DNA polymerase | |||||||
|---|---|---|---|---|---|---|---|
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| 識別碼 | |||||||
| EC編號 | 2.7.7.7 | ||||||
| CAS號 | 9012-90-2 | ||||||
| 數據庫 | |||||||
| IntEnz | IntEnz瀏覽 | ||||||
| BRENDA | BRENDA入口 | ||||||
| ExPASy | NiceZyme瀏覽 | ||||||
| KEGG | KEGG入口 | ||||||
| MetaCyc | 代謝路徑 | ||||||
| PRIAM | 概述 | ||||||
| PDB | RCSB PDB PDBj PDBe PDBsum | ||||||
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DNA聚合酶δ（DNA polymerase delta）為真核生物體內的一種酶複合體，可進行DNA複製及修復。DNA聚合酶δ由四個次單元組成：POLD1、POLD2、POLD3，以及POLD4[1]。本酵素可進行延遲股及領先股的複製[2][3]。若PCNA存在，該酵素的持續效能會增強。
參考文獻
- ^ Liu G, Warbrick E. The p66 and p12 subunits of DNA polymerase delta are modified by ubiquitin and ubiquitin-like proteins. Biochem. Biophys. Res. Commun. October 2006, 349 (1): 360–6. PMID 16934752. doi:10.1016/j.bbrc.2006.08.049.
- ^ Johnson RE, Klassen R, Prakash L, Prakash S. A Major Role of DNA Polymerase δ in Replication of Both the Leading and Lagging DNA Strands. Mol. Cell. July 16, 2015, 59 (2): 163–175. PMC 4517859
. PMID 26145172. doi:10.1016/j.molcel.2015.05.038.
- ^ http://www.ncbi.nlm.nih.gov.elibrary.mdanderson.org/pubmed/?term=DNA+Polymerases+Divide+the+Labor+of+Genome+Replication[永久失效連結]
