8A-PDHQ

8A-PDHQ
識別資訊
	IUPAC命名法 8a-phenyldecahydroquinoline; ;
CAS號	131556-11-1
PubChem CID	131397;
ChemSpider	116144 ;
UNII	8GBT78N4EC;
CompTox Dashboard（英語：CompTox Chemicals Dashboard） (EPA)	DTXSID40927262 ;
化學資訊
化學式	C15H21N
摩爾質量	215.34 g·mol−1
3D模型（JSmol（英語：JSmol））	交互式圖像;
	SMILES C1([C@]23CCCC[C@H]2CCCN3)=CC=CC=C1;
	InChI InChI=1S/C15H21N/c1-2-7-13(8-3-1)15-11-5-4-9-14(15)10-6-12-16-15/h1-3,7-8,14,16H,4-6,9-12H2 ; Key:QEXADSRMRUUCQJ-UHFFFAOYSA-N ;

8A-PDHQ（全稱：8a-苯基十氫喹啉，英語：8a-Phenyldecahydroquinoline）是一種含氮有機化合物，分子式C₁₅H₂₁N，可作為NMDA受體拮抗劑，1950年代由Parke-Davis開發^[1]^[2]^[3]。

參考文獻

^ US Patent 3035059
^ Chen, C; Kozikowski, AP; Wood, PL; Reynolds, IJ; Ball, RG; Pang, YP. Synthesis and biological activity of 8a-phenyldecahydroquinolines as probes of PCP's binding conformation. A new PCP-like compound with increased in vivo potency.. Journal of medicinal chemistry. 1992-05-01, 35 (9): 1634–8. PMID 1315871. doi:10.1021/jm00087a020.
^ Elhallaoui, M; Laguerre, M; Carpy, A; Ouazzani, FC. Molecular modeling of noncompetitive antagonists of the NMDA receptor: proposal of a pharmacophore and a description of the interaction mode.. Journal of molecular modeling. 2002-02, 8 (2): 65–72. PMID 12032600. doi:10.1007/s00894-001-0067-4.