甲酚曲唑三硅氧烷

甲酚曲唑三硅氧烷
	IUPAC名; 2-(2H-Benzotriazol-2-yl)-4-methyl-6-[2-methyl-3-[1,3,3,3-tetramethyl-1-[(trimethylsilyl)oxy]-1-disiloxanyl]propyl]phenol
	系統名; 2-(2H-1,2,3-Benzotriazol-2-yl)-4-methyl-6-[2-methyl-3-(2,2,4,6,6-pentamethyl-3,5-dioxa-2,4,6-trisilaheptan-4-yl)propyl]phenol
別名	Mexoryl XL; Silatrizole
識別
CAS號	155633-54-8 ?
PubChem	9848888
ChemSpider	8024601
SMILES	CC(CC1=C(O)C(=CC(C)=C1)N1N=C2C=CC=CC2=N1)C[Si](C)(O[Si](C)(C)C)O[Si](C)(C)C;
性質
化學式	C24H39N3O3Si3
摩爾質量	501.84 g·mol−1
	若非註明，所有數據均出自標準狀態（25 ℃，100 kPa）下。

甲酚曲唑三硅氧烷（INCI：drometrizole trisiloxane）脂溶性苯並三唑衍生物。是一種防曬劑，於1989由歐萊雅開發，商品名Mexoryl XL。甲酚曲唑三硅氧烷為廣譜紫外線吸收劑，最大吸收峰為303 nm（UVB）和344 nm（UVA），其常與對苯二亞甲基二樟腦磺酸聯合作用，產生協同效應^[1]。

批准

甲酚曲唑三硅氧烷已經在歐盟^[2]、加拿大^[3]、澳大利亞^[4] 、日本^[5]等國家批准使用，但美國尚未批准。

參考文獻

^ Moyal D. Prevention of ultraviolet-induced skin pigmentation. Photodermatol Photoimmunol Photomed. October 2004, 20 (5): 243–7. PMID 15379874. S2CID 22120937. doi:10.1111/j.1600-0781.2004.00111.x.
^ COUNCIL DIRECTIVE of 27 July 1976 on the approximation of the laws of the Member States relating to cosmetic products (PDF). [2024-07-05]. （原始內容存檔 (PDF)於2008-08-14）.
^ Sunburn Protectants 網際網路檔案館的存檔，存檔日期March 11, 2009，., Health Canada
^ Australian Regulatory Guidelines for OTC Medicines - Chapter 10 (PDF). [2024-07-05]. （原始內容存檔 (PDF)於2009-10-28）.
^ Forestier, S.; Ortiz, S; Jitsukawa Setsuko. Mexoryl XL: A new UV protective agent. Fragr J. 2004, 32 (4): 59–64 [2008-08-01]. （原始內容存檔於2009-10-28）.

[1] Moyal D. Prevention of ultraviolet-induced skin pigmentation. Photodermatol Photoimmunol Photomed. October 2004, 20 (5): 243–7. PMID 15379874. S2CID 22120937. doi:10.1111/j.1600-0781.2004.00111.x.

[2] COUNCIL DIRECTIVE of 27 July 1976 on the approximation of the laws of the Member States relating to cosmetic products (PDF). [2024-07-05]. （原始內容存檔 (PDF)於2008-08-14）.

[3] Sunburn Protectants 網際網路檔案館的存檔，存檔日期March 11, 2009，., Health Canada

[4] Australian Regulatory Guidelines for OTC Medicines - Chapter 10 (PDF). [2024-07-05]. （原始內容存檔 (PDF)於2009-10-28）.

[5] Forestier, S.; Ortiz, S; Jitsukawa Setsuko. Mexoryl XL: A new UV protective agent. Fragr J. 2004, 32 (4): 59–64 [2008-08-01]. （原始內容存檔於2009-10-28）.

[1]

[2]

[3]

[4]

[5]