散亂蛋白
| Dishevelled specific domain | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| 鑑定 | |||||||||||
| 標誌 | Dishevelled | ||||||||||
| Pfam | PF02377（舊版） | ||||||||||
| InterPro | IPR003351 | ||||||||||
| PROSITE | PDOC50841 | ||||||||||
| |||||||||||
散亂蛋白（英語：Dishevelled，Dsh）是涉及鈣離子與非鈣離子Wnt信號通路的蛋白質家族。Dsh是一種胞漿內的磷酸化蛋白，作為捲曲受體的下游信號分子[1]。其得名於在果蠅中最初發現該基因時，其基因突變會導致身體和翅膀的剛毛定位錯誤[2]。
參考文獻
- ^ Penton A, Wodarz A, Nusse R. A mutational analysis of dishevelled in Drosophila defines novel domains in the dishevelled protein as well as novel suppressing alleles of axin. Genetics. June 2002, 161 (2): 747–62. PMC 1462152
. PMID 12072470.
- ^ Wallingford JB, Habas R. The developmental biology of Dishevelled: an enigmatic protein governing cell fate and cell polarity. Development. October 2005, 132 (20): 4421–36. PMID 16192308. doi:10.1242/dev.02068.
