全氟癸酸
全氟癸酸 | |
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IUPAC名 2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-nonadecafluorodecanoic acid | |
識別 | |
CAS號 | 335-76-2 |
PubChem | 9555 |
ChemSpider | 9181 |
SMILES |
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InChI |
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InChIKey | PCIUEQPBYFRTEM-UHFFFAOYSA-N |
Gmelin | 35659 |
性質 | |
化學式 | C10HF19O2 |
摩爾質量 | 514.08 g·mol−1 |
熔點 | 77-81 °C(269 K) |
沸點 | 218 °C(491 K) |
若非註明,所有數據均出自標準狀態(25 ℃,100 kPa)下。 |
全氟癸酸(英語:Perfluorodecanoic acid,縮寫PFDA)是一種全氟羧酸表面活性劑[1],工業上常用於濕潤劑和阻燃劑[2]。和其它含氟表面活性劑類似,PFDA的使用也引發了健康問題[3],限制了其使用[4]。 PFDA也可以作為研究過氧化物酶體增殖的化學探針[5][6]。
參考文獻
- ^ Reich, Ieva L.; Reich, Hans J.; Menahan, Lawrence A.; Peterson, Richard E. Synthesis of 14C-labeled perfluorooctanoic and perfluorodecanoic acids; purification of perfluorodecanoic acid. Journal of Labelled Compounds and Radiopharmaceuticals. October 1987, 24 (10): 1235–1244. doi:10.1002/jlcr.2580241011.
- ^ Harris, M. Developmental toxicity of perfluorodecanoic acid in C57BL/6N mice. Fundamental and Applied Toxicology. April 1989, 12 (3): 442–448. doi:10.1016/0272-0590(89)90018-3 (英語).
- ^ Danish study links perfluorinated chemicals to miscarriage. Chemical Watch. [25 March 2019] (英語).
- ^ Germany and Sweden propose restrictions on six PFASs. Chemical Watch. 14 May 2015 [25 March 2019]. (原始內容存檔於2022-01-19) (英語).
- ^ Vanden Heuvel, John P. Perfluorodecanoic acid as a useful pharmacologic tool for the study of peroxisome proliferation. General Pharmacology: The Vascular System. October 1996, 27 (7): 1123–1129. doi:10.1016/0306-3623(95)00126-3.
- ^ Chen, Li-Chuan; Tatum, Vickie; Glauert, Howard P.; Chow, Ching K. Peroxisome proliferator perfluorodecanoic acid alters glutathione and related enzymes. Journal of Biochemical and Molecular Toxicology. 2001, 15 (2): 107–113. ISSN 1095-6670. doi:10.1002/jbt.6 (英語).