21-脱氧皮质醇

21-脱氧皮质醇
	IUPAC名; (8S,9S,10R,11S,13S,14S,17R)-17-acetyl-11,17-dihydroxy-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
别名	21-Desoxycortisol; 21-Dehydrohydrocortisone; 21-Deoxyhydrocortisone; 11β,17α-Dihydroxyprogesterone; 11β,17α-Dihydroxypregn-4-ene-3,20-dione
识别
CAS号	641-77-0
PubChem	92827
ChemSpider	83796
SMILES	CC(=O)[C@]1(CC[C@@H]2[C@@]1(C[C@@H]([C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)O)C)O;
ChEBI	28697
KEGG	C05497
性质
化学式	C21H30O4
摩尔质量	346.46 g·mol−1
	若非注明，所有数据均出自标准状态（25 ℃，100 kPa）下。

21-脱氧皮质醇（英语：21-Deoxycortisol，也称为11β,17α-二羟基孕酮，11β,17α-dihydroxyprogesterone，或11β,17α-二羟基孕-4-烯-3,20-二酮，11β,17α-dihydroxypregn-4-ene-3,20-dione）是一种与皮质醇（11β,17α,21-三羟基孕酮）有关的天然内源性甾体物质，可由类固醇11-β-羟化酶（英语：Steroid 11-beta-hydroxylase）（CYP11B1）代谢 17α-羟孕酮生成^[1]。

参考文献

^ Cristoni S, Cuccato D, Sciannamblo M, Bernardi LR, Biunno I, Gerthoux P, Russo G, Weber G, Mora S. Analysis of 21-deoxycortisol, a marker of congenital adrenal hyperplasia, in blood by atmospheric pressure chemical ionization and electrospray ionization using multiple reaction monitoring. Rapid Commun. Mass Spectrom. 2004, 18 (1): 77–82. Bibcode:2004RCMS...18...77C. PMID 14689562. doi:10.1002/rcm.1284.

外部链接

Metabocard for 21-Deoxycortisol (HMDB04030) - Human Metabolome Database（页面存档备份，存于互联网档案馆）

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[pmid14689562-1] Cristoni S, Cuccato D, Sciannamblo M, Bernardi LR, Biunno I, Gerthoux P, Russo G, Weber G, Mora S. Analysis of 21-deoxycortisol, a marker of congenital adrenal hyperplasia, in blood by atmospheric pressure chemical ionization and electrospray ionization using multiple reaction monitoring. Rapid Commun. Mass Spectrom. 2004, 18 (1): 77–82. Bibcode:2004RCMS...18...77C. PMID 14689562. doi:10.1002/rcm.1284.

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