金胺O
| Auramine O | |||
|---|---|---|---|
| |||
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| IUPAC名 bis[4-(dimethylamino)phenyl]methaniminium chloride | |||
| 别名 | Basic yellow 2, Pyocatanium aureum, aizen auramine, Pyoktanin Yellow, Canary Yellow, Pyoktanin, or C.I. 41000 | ||
| 识别 | |||
| CAS号 | 2465-27-2 
| ||
| PubChem | 17170 | ||
| ChemSpider | 16254 | ||
| SMILES |
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| InChI |
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| InChIKey | JPIYZTWMUGTEHX-UHFFFAOYAY | ||
| 性质 | |||
| 化学式 | C17H22ClN3 | ||
| 摩尔质量 | 303.83 g·mol−1 | ||
| 熔点 | 267 °C | ||
| 危险性 | |||
| 警示术语 | R：R22 R24 R40 | ||
| 安全术语 | S：S36/37 S45 | ||
| 若非注明，所有数据均出自标准状态（25 ℃，100 kPa）下。 | |||
金胺O是一种二芳基甲烷萤光染料，常态下为黄色针状结晶。极易溶于水，易溶于乙醇。
金胺O可用于抗酸细菌（例如Mycobacterium）, 其方法类似抗酸染色法。[1] 也被当做希夫试剂的萤光版来使用。[2]
在金胺-若丹明染色法中与若丹明B一起用来给结核杆菌染色。[3][4] 同时也可用作防腐剂。
参考文献
- ^ Kommareddi S, Abramowsky C, Swinehart G, Hrabak L. Nontuberculous mycobacterial infections: comparison of the fluorescent auramine-O and Ziehl-Neelsen techniques in tissue diagnosis. Hum Pathol. 1984, 15 (11): 1085–9. PMID 6208117. doi:10.1016/S0046-8177(84)80253-1.
- ^ Khavkin T, Kudryavtseva M, Dragunskaya E, Polotsky Y, Kudryavtsev B. Fluorescent PAS-reaction study of the epithelium of normal rabbit ileum and after challenge with enterotoxigenic Escherichia coli. Gastroenterology. 1980, 78 (4): 782–90. PMID 6986320.
- ^ Truant J, Brett W, Thomas W. Fluorescence microscopy of tubercle bacilli stained with auramine and rhodamine. Henry Ford Hosp Med Bull. 1962, 10: 287–96. PMID 13922644.
- ^ Arrowood M, Sterling C. Comparison of conventional staining methods and monoclonal antibody-based methods for Cryptosporidium oocyst detection. J Clin Microbiol. 1989, 27 (7): 1490–5. PMC 267601
. PMID 2475523.
