绵腹衣酸
绵腹衣酸 | |
---|---|
IUPAC名 4-(2,4-Dihydroxy-6-pentylbenzoyl)oxy-2-hydroxy-6-pentylbenzoic acid | |
识别 | |
CAS号 | 641-68-9 |
PubChem | 12306720 |
ChemSpider | 31104179 |
SMILES |
|
InChI |
|
InChIKey | BEFYPHLCGVCBFF-UHFFFAOYSA-N |
ChEBI | 144192 |
性质 | |
化学式 | C24H30O7 |
摩尔质量 | 430.49 g·mol−1 |
熔点 | 122 °C(395 K) |
若非注明,所有数据均出自标准状态(25 ℃,100 kPa)下。 |
绵腹衣酸(英语:Anziaic acid)是在地衣中发现的一种缩酚酸,是橄榄酸的酯二聚体。它在C试验中呈红色反应。[1]
绵腹衣酸通过抑制拓扑异构酶发挥抗菌化合物的作用。[2][3]
绵腹衣酸存在于梅花衣科的一些物种中,包括双歧根属、[2]珊瑚枝衣属、[4]斑叶属等。[5]
生产
绵腹衣酸可以由人工合成,由橄榄酸通过O-苯酚位置的苄基化,然后与三氟乙酸酐缩合。[1]
性质
绵腹衣酸是无色的,能溶于乙醇、乙醇-水混合物或环己烷-苯混合物。[1]
相关化合物
珠光酸、dihydroprolichenic acid、绵腹衣酸-2'-O-甲醚、珠光酸-2-O-甲醚、珠光酸-2'-O-甲醚和planaic acid是绵腹衣酸的衍生物。[1]
参考资料
- ^ 1.0 1.1 1.2 1.3 Elix, J. A. Synthesis of para-olivetol depsides. Australian Journal of Chemistry. 1974, 27 (8): 1767. doi:10.1071/CH9741767.
- ^ 2.0 2.1 Cheng, Bokun; Cao, Shugeng; Vasquez, Victor; Annamalai, Thirunavukkarasu; Tamayo-Castillo, Giselle; Clardy, Jon; Tse-Dinh, Yuk-Ching. Identification of Anziaic Acid, a Lichen Depside from Hypotrachyna sp., as a New Topoisomerase Poison Inhibitor. PLOS ONE. 8 April 2013, 8 (4): e60770. Bibcode:2013PLoSO...860770C. PMC 3620467 . PMID 23593306. doi:10.1371/journal.pone.0060770 .
- ^ Kekuda, T.R Prashith; Lavanya, D .; Pooja, Rao. Lichens as promising resources of enzyme inhibitors: A review. Journal of Drug Delivery and Therapeutics. March 2019, 9 (2S). doi:10.22270/jddt.v9i2-s.2546 (不活跃 31 January 2024).
- ^ Ramaut, J. L.; Serusiaux, E.; Brouers, M.; Corvisier, M. Lichen Acids of the Stereocaulon ramulosum Group in Central East Africa. The Bryologist. 1978, 81 (3): 415. JSTOR 3242244. doi:10.2307/3242244.
- ^ Mark, Kristiina; Randlane, Tiina; Thor, Göran; Hur, Jae-Seoun; Obermayer, Walter; Saag, Andres. Lichen chemistry is concordant with multilocus gene genealogy in the genus Cetrelia (Parmeliaceae, Ascomycota). Fungal Biology. 2019, 123 (2): 125–139. PMID 30709518. S2CID 73439650. doi:10.1016/j.funbio.2018.11.013.