3-碘-6-甲基喹啉
3-碘-6-甲基喹啉 | |
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识别 | |
CAS号 | 1424246-00-3 ![]() |
性质 | |
化学式 | C10H8IN |
摩尔质量 | 269.08 g·mol−1 |
外观 | 白色固体[1]或浅黄色固体[2] |
熔点 | 112-113 °C[1] 106-108 °C[2] |
若非注明,所有数据均出自标准状态(25 ℃,100 kPa)下。 |
3-碘-6-甲基喹啉是一种有机化合物,化学式为C10H8IN。它可由6-甲基喹啉和过氧化叔丁醇、碘的反应制得。[3]它和苯乙炔在三乙胺存在下、碘化亚铜和二氯双(三苯基膦)钯催化下于乙腈中反应,可以得到6-甲基-3-苯乙炔基喹啉。[4]它和二氧化硒加热反应,可以得到3-碘喹啉-6-甲醛。[5]
参考文献
- ^ 1.0 1.1 Kai Sun, Yunhe Lv, Junjie Wang, Jingjing Sun, Lulu Liu, Mingyang Jia, Xin Liu, Zhenduo Li, Xin Wang. Regioselective, Molecular Iodine-Mediated C3 Iodination of Quinolines. Organic Letters. 2015-09-18, 17 (18): 4408–4411 [2023-03-04]. ISSN 1523-7060. doi:10.1021/acs.orglett.5b01857. (原始内容存档于2023-03-04) (英语).
- ^ 2.0 2.1 Imran Kazi, Somraj Guha, Govindasamy Sekar. Halogen Bond-Assisted Electron-Catalyzed Atom Economic Iodination of Heteroarenes at Room Temperature. The Journal of Organic Chemistry. 2019-06-07, 84 (11): 6642–6654 [2023-03-04]. ISSN 0022-3263. doi:10.1021/acs.joc.9b00174. (原始内容存档于2023-03-04) (英语).
- ^ Krishna K. Sharma, Dhananjay I. Patel, Rahul Jain. Metal-free synthesis of N-fused heterocyclic iodides via C–H functionalization mediated by tert-butylhydroperoxide. Chemical Communications. 2015, 51 (82): 15129–15132 [2023-03-04]. ISSN 1359-7345. doi:10.1039/C5CC04013B (英语).
- ^ Runfa He, Yang Liu, Yingqi Feng, Lu Chen, Yubing Huang, Feng Xie, Yibiao Li. Access to Thienopyridine and Thienoquinoline Derivatives via Site-Selective C–H Bond Functionalization and Annulation. Organic Letters. 2022-05-06, 24 (17): 3167–3172 [2023-03-04]. ISSN 1523-7060. doi:10.1021/acs.orglett.2c00903. (原始内容存档于2023-03-04) (英语).
- ^ Willms, Lothar; et al. Preparation of nitrogen-containing heterocyclic compounds for plant disease control. 2014 WO 2014048940 A2.