铁屎米-6-酮

铁屎米-6-酮
英文名	Canthin-6-one
别名	6-铁屎米酮
识别
CAS号	479-43-6
SMILES	O=C1C=CC2=NC=CC=3C4=CC=CC=C4N1C23;
性质
化学式	C14H8N2O
摩尔质量	220.23 g·mol−1
外观	白色晶体
熔点	161~163 °C
	若非注明，所有数据均出自标准状态（25 ℃，100 kPa）下。

铁屎米-6-酮（6H-吲哚并[3,2,1-de][1,5]萘啶-6-酮）是一种有机化合物，化学式为C₁₄H₈N₂O。它可由8-(2-氯苯基)-1,5-萘啶-2-酮和碳酸铯在N,N'-二甲基乙二胺和碘化亚铜的催化下反应制得。^[2]它在钯催化下加氢，可以得到4,5-二氢铁屎米-6-酮；它也可以被mCPBA氧化为铁屎米-6-酮-N-氧化物。^[1]

参考文献

^ ^1.0 ^1.1 ^1.2 Gerardo Cebrián-Torrejón, Nicolas Mackiewicz, Rafael P. Vázquez-Manrique, Alain Fournet, Bruno Figadère, Julien Nicolas, Erwan Poupon. Solution Phase and Nanoparticular Biosynthetically Inspired Interconnections in the Canthin-6-one β-Carboline Series and Study of Phenotypic Properties on C. elegans. European Journal of Organic Chemistry. 2013. 26. 5821-5828. doi:10.1002/ejoc.201300770.
^ Gollner, Andreas; Koutentis, Panayiotis A. Two-Step Total Syntheses of Canthin-6-one Alkaloids: New One-Pot Sequential Pd-Catalyzed Suzuki−Miyaura Coupling and Cu-Catalyzed Amidation Reaction. Organic Letters (2010), 12 (6), 1352-1355. doi:10.1021/ol100300s.

[Gerardo-1] 1.0 ^1.1 ^1.2 Gerardo Cebrián-Torrejón, Nicolas Mackiewicz, Rafael P. Vázquez-Manrique, Alain Fournet, Bruno Figadère, Julien Nicolas, Erwan Poupon. Solution Phase and Nanoparticular Biosynthetically Inspired Interconnections in the Canthin-6-one β-Carboline Series and Study of Phenotypic Properties on C. elegans. European Journal of Organic Chemistry. 2013. 26. 5821-5828. doi:10.1002/ejoc.201300770.

[2] Gollner, Andreas; Koutentis, Panayiotis A. Two-Step Total Syntheses of Canthin-6-one Alkaloids: New One-Pot Sequential Pd-Catalyzed Suzuki−Miyaura Coupling and Cu-Catalyzed Amidation Reaction. Organic Letters (2010), 12 (6), 1352-1355. doi:10.1021/ol100300s.

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