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绒毛膜促性腺激素β亚基

维基百科,自由的百科全书
Chorionic gonadotropin, beta polypeptide
绒毛膜促性腺激素,β多肽
PDB rendering based on 1hcn.
有效结构
PDB 直系同源检索:PDBe, RCSB
标识
代号 CGB; CGB3; CGB5; CGB7; CGB8; hCGB
扩展标识 遗传学118860 同源基因37338 GeneCards: CGB Gene
直系同源体
物种 人类 小鼠
Entrez 1082 n/a
Ensembl ENSG00000104827 n/a
UniProt P01233 n/a
mRNA序列 NM_000737 n/a
蛋白序列 NP_000728 n/a
基因位置 Chr 19:
49.53 – 49.53 Mb
n/a
PubMed查询 [1] n/a

绒毛膜促性腺激素β亚基(英語:Choriogonadotropin subunit beta,CG-beta,也被称为绒毛膜促性腺激素,β肽链 chorionic gonadotrophin chain beta) 是一个由人类基因CGB 编码的蛋白质[1][2][3]

β肽链的145个氨基酸残基的序列为:

NH2 - Ser - Lys - Glu - Pro - Leu - Arg - Pro - Arg - Cys - Arg - Pro - Ile - Asn - Ala - Thr - Leu - Ala - Val - Glu - Lys - Glu - Gly - Cys - Pro - Val - Cys - Ile - Thr - Val - Asn - Thr - Thr - Ile - Cys - Ala - Gly - Tyr - Cys - Pro - Thr - Met - Thr - Arg - Val - Leu - Gln - Gly - Val - Leu - Pro - Ala - Leu - Pro - Gln - Val - Val - Cys - Asn - Tyr - Arg - Asp - Val - Arg - Phe - Glu - Ser - Ile - Arg - Leu - Pro - Gly - Cys - Pro - Arg - Gly - Val - Asn - Pro - Val - Val - Ser - Tyr - Ala - Val - Ala - Leu - Ser - Cys - Gln - Cys - Ala - Leu - Cys - Arg - Arg - Ser - Thr - Thr - Asp - Cys - Gly - Gly - Pro - Lys - Asp - His - Pro - Leu - Thr - Cys - Asp - Asp - Pro - Arg - Phe - Gln - Asp - Ser - Ser - Ser - Ser - Lys - Ala - Pro - Pro - Pro - Ser - Leu - Pro - Ser - Pro - Ser - Arg - Leu - Pro - Gly - Pro - Ser - Asp - Thr - Pro - Ile - Leu - Pro - Gln - COOH

参考文献

  1. ^ Entrez Gene: chorionic gonadotropin. 
  2. ^ Fiddes JC, Goodman HM. The cDNA for the beta-subunit of human chorionic gonadotropin suggests evolution of a gene by readthrough into the 3'-untranslated region. Nature. August 1980, 286 (5774): 684–7. PMID 6774259. doi:10.1038/286684a0. 
  3. ^ Policastro P, Ovitt CE, Hoshina M, Fukuoka H, Boothby MR, Boime I. The beta subunit of human chorionic gonadotropin is encoded by multiple genes. J. Biol. Chem. October 1983, 258 (19): 11492–9. PMID 6194155. 

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