文殊兰碱

文殊兰碱
别名	Crinidine
识别
CAS号	510-67-8
PubChem	398937
SMILES	C1CN2CC3=CC4=C(C=C3[C@]15[C@H]2C[C@H](C=C5)O)OCO4;
性质
化学式	C16H17NO3
摩尔质量	271.31 g·mol−1
	若非注明，所有数据均出自标准状态（25 ℃，100 kPa）下。

文殊兰碱是一种生物鹼，存在于包括石蒜科的多种植物中。它在20世纪50年代首次在文殊蘭屬的几种植物中被分离出来，并由此得名。^[1]^[2]^[3]

有多篇文献报道了它的合成方法。^[4]^[5]^[6]^[7]

参考文献

^ Boit, Hans-G. Über die Alkaloide von Nerine sarniensis, Crinum Moorei, Hippeastrum vittatum und Clivia miniata (VI. Mitteil. über Amaryllidaceen-Alkaloide). Chemische Berichte. 1954, 87 (11): 1704–1707. doi:10.1002/cber.19540871115.
^ Mason, L. H.; Puschett, E. R.; Wildman, W. C. Alkaloids of the Amaryllidaceae. IV. Crystalline Alkaloids of Ammocharis coranica (Ker-Gawl.) Herb., Brunsvigia rosea (Lam.) Hannibal and Two Crinum Species. Journal of the American Chemical Society. 1955, 77 (5): 1253–1256. doi:10.1021/ja01610a046.
^ Boit, Hans-G.; Ehmke, Horst. Alkaloide von Sprekelia formosissima, Galanthus Elwesii, Zephyranthes candida und Crinum Powellii (VIII. Mitteil. über Amaryllidaceen-Alkaloide¹⁾). Chemische Berichte. 1955, 88 (10): 1590–1594. doi:10.1002/cber.19550881019.
^ Muxfeldt, Hans; Schneider, Richard S.; Mooberry, Jared B. A Total Synthesis of (±)-Crinine. Journal of the American Chemical Society. 1966, 88 (15): 3670–3671. doi:10.1021/ja00967a052.
^ Martin, Stephen F.; Campbell, Carlton L. Total syntheses of (.+-.)-crinine and (.+-.)-buphanisine. The Journal of Organic Chemistry. 1988, 53 (14): 3184–3190. doi:10.1021/jo00249a011.
^ Whitlock, Howard W.; Smith, Gary Lee. Total synthesis of DL-crinine. Journal of the American Chemical Society. 1967, 89 (14): 3600–3606. doi:10.1021/ja00990a045.
^ Bru, Claire; Guillou, Catherine. Total syntheses of crinine and related alkaloids. Tetrahedron. 2006, 62 (38): 9043–9048. doi:10.1016/j.tet.2006.07.005.

[1] Boit, Hans-G. Über die Alkaloide von Nerine sarniensis, Crinum Moorei, Hippeastrum vittatum und Clivia miniata (VI. Mitteil. über Amaryllidaceen-Alkaloide). Chemische Berichte. 1954, 87 (11): 1704–1707. doi:10.1002/cber.19540871115.

[2] Mason, L. H.; Puschett, E. R.; Wildman, W. C. Alkaloids of the Amaryllidaceae. IV. Crystalline Alkaloids of Ammocharis coranica (Ker-Gawl.) Herb., Brunsvigia rosea (Lam.) Hannibal and Two Crinum Species. Journal of the American Chemical Society. 1955, 77 (5): 1253–1256. doi:10.1021/ja01610a046.

[3] Boit, Hans-G.; Ehmke, Horst. Alkaloide von Sprekelia formosissima, Galanthus Elwesii, Zephyranthes candida und Crinum Powellii (VIII. Mitteil. über Amaryllidaceen-Alkaloide¹⁾). Chemische Berichte. 1955, 88 (10): 1590–1594. doi:10.1002/cber.19550881019.

[4] Muxfeldt, Hans; Schneider, Richard S.; Mooberry, Jared B. A Total Synthesis of (±)-Crinine. Journal of the American Chemical Society. 1966, 88 (15): 3670–3671. doi:10.1021/ja00967a052.

[5] Martin, Stephen F.; Campbell, Carlton L. Total syntheses of (.+-.)-crinine and (.+-.)-buphanisine. The Journal of Organic Chemistry. 1988, 53 (14): 3184–3190. doi:10.1021/jo00249a011.

[6] Whitlock, Howard W.; Smith, Gary Lee. Total synthesis of DL-crinine. Journal of the American Chemical Society. 1967, 89 (14): 3600–3606. doi:10.1021/ja00990a045.

[7] Bru, Claire; Guillou, Catherine. Total syntheses of crinine and related alkaloids. Tetrahedron. 2006, 62 (38): 9043–9048. doi:10.1016/j.tet.2006.07.005.

[1]

[2]

[3]

[4]

[5]

[6]

[7]