井冈霉素
井冈霉素 | |
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IUPAC名 (1R,2R,3S,4S,6R)-2,3-Dihydroxy-6-(hydroxymethyl)-4-{[(1S,4S,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}cyclohexyl β-D-glucopyranoside | |
系统名 (2R,3R,4S,5S,6R)-2[(1R,2R,3S,4S,6R)-2,3-Dihydroxy-6-(hydroxymethyl)-4-{[(1S,4S,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}cyclohexyl]oxy6-(hydroxymethyl)oxane-3,4,5-triol | |
别名 | Validamycin A; Valimon; Validacin |
识别 | |
CAS号 | 37248-47-8 |
PubChem | 443629 |
ChemSpider | 16736085 |
SMILES |
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InChI |
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InChIKey | JARYYMUOCXVXNK-IMTORBKUBD |
ChEBI | 29703 |
KEGG | C12112 |
性质 | |
化学式 | C20H35NO13 |
摩尔质量 | 497.49 g·mol−1 |
若非注明,所有数据均出自标准状态(25 ℃,100 kPa)下。 |
井冈霉素(也称为有效霉素,英語:Validamycin)是一种含氮有机化合物,分子式C20H25NO13,是一种抗生素和杀真菌剂,最初由沈寅初发现自链霉菌属的吸水链霉菌(Streptomyces hygroscopicus),可抑制海藻糖酶[1],用于防治水稻纹枯病。
参考文献
- ^ Li, H.; Su, H.; Kim, S. B.; Chang, Y. K.; Hong, S. K.; Seo, Y. G.; Kim, C. J. Enhanced production of trehalose in Escherichia coli by homologous expression of otsBA in the presence of the trehalase inhibitor, validamycin A, at high osmolarity. Journal of Bioscience and Bioengineering. 2011, 113 (2): 224–32. PMID 22036231. doi:10.1016/j.jbiosc.2011.09.018.