默克尔神经末梢(英文:Merkel nerve ending),又称默克尔触觉盘(Merkel's tactile disk)或默克尔盘(Merkel's disk),是一种缓慢调节的力学感受器,位于表皮基底层与毛囊中[1][2][3]。默克尔神经末梢以德国科学家弗里德里希·西格蒙德·默克尔的名字命名。它们能感知机械压力和位置,也能通过深层静态触碰进行特征感知,譬如感知形状和边缘[1]。
默克尔细胞位于表皮基底层,储存血清素,并在感知压力时释放至相应的神经末梢[3][4]。每个末梢都由一个默克尔细胞与一个邻近神经终端的组成,因此被称为“默克尔细胞-神经突复合体(Merkel cell–neurite complex)”或默克尔触觉盘[1][5]。单个传入神经纤维可支配约90个此种神经末梢。
参见
参考资料
- ^ 1.0 1.1 1.2 Purves, Dale; Augustine, George J.; Fitzpatrick, David; Katz, Lawrence C.; LaMantia, Anthony-Samuel; McNamara, James O.; Williams, S. Mark. Mechanoreceptors Specialized to Receive Tactile Information. Neuroscience. 2nd edition. 2001 [2021-02-21]. (原始内容存档于2021-05-06) (英语).
- ^ Merkel's tactile disk. APA Dictionary of Psychology. [2021-02-21]. (原始内容存档于2018-04-27) (英语).
- ^ 3.0 3.1 Zdenek Halata, Milos Grim & Klaus I Baumann. Current understanding of Merkel cells, touch reception and the skin. Expert Rev. Dermatol. 2010, 5 (1): 109–116.
- ^ Chang, Weipang; Kanda, Hirosato; Ikeda, Ryo; Ling, Jennifer; DeBerry, Jennifer J.; Gu, Jianguo G. Merkel disc is a serotonergic synapse in the epidermis for transmitting tactile signals in mammals. Proceedings of the National Academy of Sciences. 2016-09-13, 113 (37): E5491–E5500 [2021-02-21]. ISSN 0027-8424. PMID 27573850. doi:10.1073/pnas.1610176113. (原始内容存档于2021-03-01) (英语).
- ^ Woo, Seung-Hyun; Lumpkin, Ellen A.; Patapoutian, Ardem. Merkel cells and neurons keep in touch. Trends in cell biology. 2015-2, 25 (2): 74–81. ISSN 0962-8924. PMC 4312710
. PMID 25480024. doi:10.1016/j.tcb.2014.10.003.